DIP logo Database of Interacting Proteins IMEx logo
Jobs
Help
News
Register
Statistics
Satellites
SEARCH
SUBMIT
Software
Services
Articles
Links
Files
MIF
[DLRP home] [Help][LOGIN]

Database of Ligand-Receptor Pairs


Results are listed for human genes.
Use HomoloGene to find homologs in other organisms.

Ligand Receptor DIP interaction links Notes
SCYA18
Hs.16530
small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
   
SCYA11
Hs.54460
small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
DIP:5858N
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10393E 
GPR9
Hs.198252
G protein-coupled receptor 9
DIP:5891N
DIP:10524Eweak
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10466Eweak
CCBP2
Hs.117572
chemokine binding protein 2
 weak
SCYA24
Hs.247838
small inducible cytokine subfamily A (Cys-Cys), member 24
DIP:5876N
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10472E 
SCYA23
Hs.169191
small inducible cytokine subfamily A (Cys-Cys), member 23
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
  
SCYA14
Hs.20144
small inducible cytokine subfamily A (Cys-Cys), member 14
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
  
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA16
Hs.10458
small inducible cytokine subfamily A (Cys-Cys), member 16
DIP:5831N
   
SCYA26
Hs.131342
small inducible cytokine subfamily A (Cys-Cys), member 26
DIP:5877N
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10476E 
SCYA3
Hs.73817
small inducible cytokine A3 (homologous to mouse Mip-1a)
DIP:5837N
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10358E 
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10421E 
SCYA4
Hs.75703
small inducible cytokine A4 (homologous to mouse Mip-1b)
DIP:5840N
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10451E 
CCR8
Hs.113222
chemokine (C-C motif) receptor 8
DIP:5836N
 weak
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10359Eweak
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA15
Hs.272493
small inducible cytokine subfamily A (Cys-Cys), member 15
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
  
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
  
SCYA1
Hs.72918
small inducible cytokine A1 (I-309, homologous to mouse Tca-3)
DIP:5835N
CCR8
Hs.113222
chemokine (C-C motif) receptor 8
DIP:5836N
DIP:10354E 
SCYA21
Hs.57907
small inducible cytokine subfamily A (Cys-Cys), member 21
DIP:5854N
CCR7
Hs.1652
chemokine (C-C motif) receptor 7
  
GPR9
Hs.198252
G protein-coupled receptor 9
DIP:5891N
 weak
SCYA5
Hs.241392
small inducible cytokine A5 (RANTES)
DIP:5841N
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10360E 
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10380E 
CCR4
Hs.184926
chemokine (C-C motif) receptor 4
DIP:5848N
  
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10461E 
FY
Hs.183
Duffy blood group
DIP:3783N
 nonsignaling
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA2
Hs.303649
small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
DIP:5838N
CCR2
Hs.395
chemokine (C-C motif) receptor 2
DIP:5833N
DIP:5839N
DIP:10420E
DIP:10357E
 
FY
Hs.183
Duffy blood group
DIP:3783N
 nonsignaling
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10455Eweak
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA8
Hs.271387
small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
DIP:5871N
CCR2
Hs.395
chemokine (C-C motif) receptor 2
DIP:5833N
DIP:5839N
DIP:10454E 
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
  
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10452E 
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10453E 
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA27
Hs.225948
small inducible cytokine subfamily A (Cys-Cys), member 27
DIP:5872N
GPR2
Hs.278446
G protein-coupled receptor 2
DIP:5873N
DIP:10456E 
SCYA7
Hs.251526
small inducible cytokine A7 (monocyte chemotactic protein 3)
DIP:5847N
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
DIP:10381E 
CCR2
Hs.395
chemokine (C-C motif) receptor 2
DIP:5833N
DIP:5839N
DIP:10450E 
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10474E 
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10462Eantagonist
CCBP2
Hs.117572
chemokine binding protein 2
 weak
SCYA13
Hs.11383
small inducible cytokine subfamily A (Cys-Cys), member 13
DIP:5874N
CCR2
Hs.395
chemokine (C-C motif) receptor 2
DIP:5833N
DIP:5839N
DIP:10539E 
CCR3
Hs.158324
chemokine (C-C motif) receptor 3
DIP:5846N
DIP:10473E 
CCR1
Hs.301921
chemokine (C-C motif) receptor 1
DIP:5832N
  
CCR5
Hs.54443
chemokine (C-C motif) receptor 5
DIP:5866N
DIP:10463Eweak
CCBP2
Hs.117572
chemokine binding protein 2
  
SCYA17
Hs.66742
small inducible cytokine subfamily A (Cys-Cys), member 17
DIP:5842N
CCR4
Hs.184926
chemokine (C-C motif) receptor 4
DIP:5848N
DIP:10382E 
CCR8
Hs.113222
chemokine (C-C motif) receptor 8
DIP:5836N
DIP:10362Eweak
SCYA20
Hs.75498
small inducible cytokine subfamily A (Cys-Cys), member 20
DIP:5864N
CCR6
Hs.46468
chemokine (C-C motif) receptor 6
DIP:5865N
DIP:10419E 
SCYA19
Hs.50002
small inducible cytokine subfamily A (Cys-Cys), member 19
DIP:5857N
CCR7
Hs.1652
chemokine (C-C motif) receptor 7
  
SCYA25
Hs.50404
small inducible cytokine subfamily A (Cys-Cys), member 25
DIP:5883N
CCR9
Hs.225946
chemokine (C-C motif) receptor 9
  
SCYA22
Hs.97203
small inducible cytokine subfamily A (Cys-Cys), member 22
DIP:5849N
CCR4
Hs.184926
chemokine (C-C motif) receptor 4
DIP:5848N
DIP:10383E 
IL8
Hs.624
interleukin 8
DIP:3778N
IL8RA
Hs.194778
interleukin 8 receptor, alpha
DIP:3779N
DIP:5745E 
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:5748E 
FY
Hs.183
Duffy blood group
DIP:3783N
DIP:5750Enonsignaling
SCYB6
Hs.164021
small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
IL8RA
Hs.194778
interleukin 8 receptor, alpha
DIP:3779N
  
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
  
MIG
Hs.77367
monokine induced by gamma interferon
GPR9
Hs.198252
G protein-coupled receptor 9
DIP:5891N
  
SDF1
Hs.237356
stromal cell-derived factor 1
DIP:5894N
CXCR4
Hs.89414
chemokine (C-X-C motif), receptor 4 (fusin)
  
SCYB11
Hs.103982
small inducible cytokine subfamily B (Cys-X-Cys), member 11
GPR9
Hs.198252
G protein-coupled receptor 9
DIP:5891N
  
PF4
Hs.81564
platelet factor 4
   
SCYB5
Hs.89714
small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78)
DIP:5911N
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:10571E 
IL8RA
Hs.194778
interleukin 8 receptor, alpha
DIP:3779N
DIP:10572Eweak
SCYB10
Hs.2248
small inducible cytokine subfamily B (Cys-X-Cys), member 10
GPR9
Hs.198252
G protein-coupled receptor 9
DIP:5891N
  
PPBP
Hs.2164
pro-platelet basic protein (includes platelet basic protein, beta-thromboglobulin, connective tissue-activating peptide III, neutrophil-activating peptide-2)
DIP:5913N
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:10574E 
FY
Hs.183
Duffy blood group
DIP:3783N
 nonsignaling
GRO1
Hs.789
GRO1 oncogene (melanoma growth stimulating activity, alpha)
DIP:5896N
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:10495E 
FY
Hs.183
Duffy blood group
DIP:3783N
DIP:10564Enonsignaling
GRO2
Hs.75765
GRO2 oncogene
DIP:5908N
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:10568E 
GRO3
Hs.89690
GRO3 oncogene
DIP:5909N
IL8RB
Hs.846
interleukin 8 receptor, beta
DIP:3782N
DIP:10569E 
SCYB13
Hs.100431
small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cell chemoattractant)
DIP:5914N
BLR1
Hs.113916
Burkitt lymphoma receptor 1, GTP-binding protein
DIP:5834N
DIP:10586E 
SCYB14
Hs.24395
small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK)
   
SCYC1
Hs.3195
small inducible cytokine subfamily C, member 1 (lymphotactin)
CCXCR1
Hs.248116
chemokine (C motif) XC receptor 1
  
SCYC2
Hs.174228
small inducible cytokine subfamily C, member 2
CCXCR1
Hs.248116
chemokine (C motif) XC receptor 1
  
SCYD1
Hs.80420
small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
DIP:5878N
CX3CR1
Hs.78913
chemokine (C-X3-C) receptor 1
DIP:5879N
DIP:10477E 


Notes:

antagonist = the ligand is an antagonist for the indicated receptor
nonsignaling = the receptor binds the ligand but does not transduce an intracellular signal
weak = the ligand is a poor agonist or binds weakly to the indicated receptor

For more information regarding noted chemokines see:
Murphy, P. M., Baggiolini, M., Charo, I. F., Hebert, C. A., Horuk, R., Matsushima, K., Miller, L. H., Oppenheim, J. J., and Power, C. A. (2000). International union of pharmacology. XXII. Nomenclature for chemokine receptors, Pharmacological Reviews 52, 145-76. [PubMed]


Back to top











Copyright 1999-2003 UCLA
The DIPTM database is the property of the Regents of the University of California, and has been exclusively licensed to to Protein Pathways. The DIPTM cannot be used for commercial purposes without a license from Protein Pathways. It is forbidden to redistribute, derivatize, or encapsulate the DIPTM in another database without permission. Sale of information derived from it, whether directly or in revised form, is forbidden except by permission of UCLA and David Eisenberg.
Legal Notices Design by: LS