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DIRECT DIP/IMEx SUBMISSIONS

We are always looking for authors willing to directly deposit peer-reviewed protein interaction data into DIP. Whereas, so far, the majority of data in DIP have been entered into the database by trained DIP curators or imported from other members of the IMEx consortium we strongly encourage the authors of the primary experimental data to directly submit their results into DIP and, in effect, into all the other databases participating in IMEx. Besides making the data rapidly available to the research community it would ensure the results are accuratly described with proper identification given to each interacting protein - in our experience unabmigious and accurate identification of the proteins used in each experiment is the most time consuming and error-prone step in the curation process, often resulting in the rejection of otherwise valuable interaction data.

To submit interaction data to DIP, follow these two easy steps:
  • Format the data (using one of the tools below; MIF 2.5 XML files are preferred)
  • Email us the formatted data file
If you run into trouble, we are happy to help -- email us at dip@mbi.ucla.edu.

As we realize that describing interaction data in a highly structured format required by the IMEx agreement is not a simple task we provide access to a number of tools co-developed by the members of the IMEx consortium as well as by the HUPO-PSI community in hope to make the process as simple and user friendly as possible.

Data Preparation Tools
FormIt A simple, Web-based tool that can be used to prepare files in MIF 2.5 format which are readily accepted by all IMEx partners. FormIt, reminiscent of GenBank's BankIt pages guides the user through preparation of files containing only the very basic description of the interaction data, as defined in the MIMIx paper. It is suitable for preparation of files describing a small number of interactions reported in a typical paper targeting few interactions of one or more proteins.
MIMIx Template Submission sheet that can be used to prepare interaction data in a structured form from within the familar Microsoft Excel spreadsheet program. Excel documents prepared with the template alre also readily accepted by all the IMEx partners. This mode of data preparation is desired when larger interaction datasets are pr the author decides to provide more experimental details than it is possible within FormIt pages.
Useful links
OLS Site EBI's Ontology Lookup Service (OLS) site provides access to the most recent controlled vocabulary terms that shoud be used to annotate the interaction data.
MIF Utilities Some simple utilities, useful when preparing MIF 2.5 files. MIF viewer displays the contents of a MIF file in a human-readable format, MIF syntax checker provides information about file conformance to the formal MIF 2.5.3 syntax specification.
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